SC853327 :: ชีวเคมีโครงสร้างเชิงคอมพิวเตอร์และการออกแบบยา (2/68)

SC853327 :: ชีวเคมีโครงสร้างเชิงคอมพิวเตอร์และการออกแบบยา (2/68)

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Dernière mise à jour le 23 November 2025

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Le contenu des cours

Date de début: 24 Nov 25
Catégorie: ภาควิชาเคมี

Généralités

ตารางเรียน 2/2568

1. Introduction to computational structural biochemistry

Introduction to computational structural biochemistry slide
What is a Protein
Novel Antioxidant Protein Hydrolysates from Mung Bean (Vigna radiate): Structural Elucidation, Antioxidant Activity, and Molecular Docking Study
Role and structure of the small subunit forming heterodimers with laccase-like enzymes

2. Enzyme structure and function

Enzyme structure and function slide
How Enzymes Work
UCSF Chimera program
UCSF Chimera tutorial
Assignments submission; enzyme structure

3. Experimental structure determination

Experimental structure determination slide
Structural insight into the catalytic mechanism of the bifunctional enzyme L-fucokinase/GDP-fucose pyrophosphorylase
Assignments submission; experimental structure determination

4. Structural bioinformatics

Structural bioinformatics slide
From DNA to protein
Deciphering the unique autoregulatory mechanisms and substrate specificity of the understudied DCLK3 kinase linked to neurodegenerative diseases

5. Protein structure prediction

Protein structure prediction slide
Swissmodel
Assignments submission; protein structure prediction

6. Protein-Target interactions

Protein-Target interactions slide
SwissDock
SwissDock tutorials
Example result website
Output files
Assignments submission; protein-target interactions

7. Computational protein design

Computational protein design slide
HPEPDOCK
Input/Output files
Assignments submission; computational protein design

8. Introduction to molecular dynamics simulation of protein

Introduction to MD of protein slide
Molecular dynamics simulation of the interaction of food proteins with small molecules

9. Foundations of protein modeling: AI and QSAR approaches

Foundations of protein modeling: AI and QSAR approaches slide
Identification of Novel JAK2 Inhibitors from Amino Derivatives of Epoxyalantolactone: In Silico and In Vitro Studies
AI-Integrated QSAR Modeling for Enhanced Drug Discovery: From Classical Approaches to Deep Learning and Structural Insight
Assignments submission

10. Drug discovery and design

Drug discovery and design slide

11. Drug target identification and validation

Drug target identification and validation slide
Assignments submission

12. Structure and ligand-based drug design

Structure and ligand-based drug design slide
High-throughput screening and characterization of novel inhibitors targeting HIV-1 protease precursor autoprocessing

13. Virtual screening and lead discovery

Virtual screening and lead discovery slide
Structural mechanism of human HCN1 hyperpolarizationactivated channel inhibition by ivabradine
Assignments submission

14. Applications of bioinformatics in protein research

Assignments submission
Computational approaches to druggable site identification: Current status and future perspective

15. Presentation

Assignments submission

À propos de l'instructeur

Picture of กมลพรรณ เสนาชัย

4524 Élèves
45 Cours

กมลพรรณ เสนาชัย

kamosa

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SC853327 :: ชีวเคมีโครงสร้างเชิงคอมพิวเตอร์และการออกแบบยา (2/68)

Teacher: อ.กมลพรรณ เสนาชัย

Skill Level: Beginner

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Prix LIBRE

Inscrivez-vous maintenant

Dernière mise à jour le 23 November 2025

7 Étudiant inscrits
46 Ressource téléchargeables

Caractéristiques du cours

Conférences16
Date de début24 Nov 2025
Niveau de compétence Débutant
Langue English
Évaluations Yes

Balise

Pas de balises.