Topic outline

• General
  

  General

   

  

   

                 MD567 712 Cell and Molecular Biology 3(3-0-6)

  Responsibility :    Academic affairs, Faculty of Medicine, Khon Kaen University

  Semester :           First semester, Academic Year 2024

  Course organizer :    

  
  

  
  

  Venue :                  Post-grad room (2^nd Floor), Faculty of Medicine, Khon Kaen University

  Monday          1-4 pm.                 

                                  Wednesday    9 am. - 12 pm.    
                                  Thursday        9 am. - 12 pm.    

  
  

  Examination:         Onsite --> Final Exam  --> Wednesday 14th August 2024,9.00 am-12.00 am @Examination room 7th floor

   ** All students must arrive at the examination room at least 15 minutes before the exam. Please also bring your identification card (ID card, passport, or student id card) to be identified.  Good luck with your exam.

  Program Schedule:      Monday (01.00-04.00 p.m.),
  

                                           Wednesday, Thursday (09:00-12:00 a.m.)

  Class :                          Graduate students

  Language :                    English

  Please join the group on Line: Group name => MD567712_1st 2024 (student)

  
  

  PDF or PowerPoints or links related to each teaching topic will be uploaded at least 3 days before that lecture by each lecturer. 

  Exam points will be posted after 50% of student help us evaluate course instructors and evaluation of the course for the final exam points.

  

   
• Evaluation 2022
  

  Evaluation 2022

  Not available
• Course orientation
  

  Course orientation

  Course orientation    

  -Course overview
• Introduction to Cell and Molecular Biology
  

  Introduction to Cell and Molecular Biology

  Introduction to Cells and Molecular Biology
  

  • M 17^th June 2024 : 13.00 - 14.00

  • Asst. Prof. Dr. Chadamas Sakonsinsiri (schadamas@kku.ac.th)

  
  

  

  
  
• Topic 1 Bioenergetics
  

  Topic 1 Bioenergetics

   1. Bioenergetics (2)

  • M 17th June 2024 , 14.00 - 16.00  

  • Assoc.Prof.Dr.Patcharee Boonsiri (patcha_b@kku.ac.th)

                            

  This topic has 4 parts. 

  Part 1 Thermodynamics in biological system

  Part 2 High energy phosphate compound

  Part 3 Oxidation-reduction in biological system

  Part 4 Energy in oxidative phosphorylation

  
  

  • Bioenergetics_2023 File 3.1MB PDF document Uploaded 16/06/23, 12:21
  • Pre-test bioenergetics_2023 URL
  • Post-test bioenergetics_2023 URL
• Topic 2. Biomolecules: Structures, Functions and Interaction
  

  Topic 2. Biomolecules: Structures, Functions and Interaction

  2. Biomolecules: Structures, Functions and Interactions (2)

  • W 19^th June 2024 : 09:00-11:00

  • Asst.Prof.Dr.Chadamas Sakonsinsiri (schadamas@kku.ac.th)
    

  

  2.1 Biomolecules & stereochemistry
  

  2.2 Molecular interactions

  2.3 Structure and function of amino acids & proteins

  2.4 Structures and functions of nucleosides, nucleotides & nucleic acids

  2.5 Structures and functions of sugars & polysaccharides

  2.6 Structures and functions of lipids and membranes

  • Post-test Biomolecules AY2023 URL

    Please complete this post-test and submit it by Friday, 23 June 2023, 18:00. If you have any question, please feel free to send me an e-mail via schadamas@kku.ac.th. Thank you.

    
    

  • Biomolecules 2023 File
  • Slide #37 corrections D-glucose and L-glucose File
• Topic 3. Metabolisms
  

  Topic 3. Metabolisms

  3. Metabolisms (2)

  • TH 20^th June 2024 : 09:00-11:00

  • Assoc.Prof. Dr.Kulthida Vaeteewoottacharn (kulthidava@kku.ac.th)
    

  
  

  3.1 Metabolic concepts in plants and animals

  3.2 Mammalian fuel metabolism: integration and regulation

  3.3 Nucleotide metabolism
  

  • Handout for Metabolism 2023 File 10.2MB PDF document Uploaded 30/06/22, 03:11
  • Self-evaluated test for Metabolism part Quiz

    The test will be available until 30 June 2023 at midnight.

    There are 10 matching points. Please complete the sentences within 10 minutes.

    The test will be automatically submitted.

• Topic 4. Genome and gene regulation
  

  Topic 4. Genome and gene regulation

  4. Genome and gene regulation (5)

  • M 24^th June 2024 : 13.00-16.00

  • W 26^th June 2024 : 09.00-11.00

  • Asst.Prof.Charupong Saengboonmee (charusa@kku.ac.th)

  
  
  

  4.1 Genome structure and evolution

  4.2 DNA and RNA synthesis and processing

  4.3 Synthesis, processing and targeting of proteins

  4.4 Control of gene expression
  

  • Handout_Genome structure and Evolution File 2.5MB PDF document Uploaded 25/06/23, 11:52
  • Handout_DNA structure and Replication File 2.7MB PDF document Uploaded 25/06/23, 22:53
  • Handout_RNA and RNA processing File 1.6MB PDF document Uploaded 26/06/23, 01:22
  • Handout_Protein Synthesis File 2.9MB PDF document Uploaded 27/06/23, 00:40
  • Handout_Regulation of Gene expression File 2.1MB PDF document Uploaded 27/06/23, 00:41
• Questions and Answers (for topics 1-4)
  

  Questions and Answers (for topics 1-4)

  Not available
• Exam 1: Topics 1-4
  

  Exam 1: Topics 1-4

  Exam 1 for topics 1-4    Bioenergetics-Genome and gene regulation (1hr lectures *5= 55 points) 
  

  
  

  • M 1^st July 2024 : 13.00-16.00

  • Asst.Prof.Dr.Opal Pitaksakulrat (opalpi@kku.ac.th)
  • Dr. Malinee Thanee  (malitha@kku.ac.th)
  • Venue: examination room, Research Laboratory Building, 7^th floor
    

  
  

  • List of students for exam 1 (1/2566) File
  • EXAM-1 Results Announcement 2023 File 408.8KB PDF document Uploaded 11/07/23, 14:59

    TOTAL         55
    AVERAGE 34.13
    MAX         51.5
    MIN                 12.75
    enrolled student 19
    

    
    

• Topic 5. Cell structure
  

  Topic 5. Cell structure

  5. Cell structure 

     5.1 Prokaryotic and eukaryotic cells

  • W 3^rdJuly 2024 : 09:00-10:00

  • Assoc.Prof.Dr. Kiatichai Faksri (kiatichai@kku.ac.th)

  
  

  • VDO clip teaching record: cell structure_with Assignment File 90.3MB Video file (MP4) Uploaded 4/08/21, 08:31
  • Prokaryotes and Eukaryotes By Kiatichai Faksri File
  • Reading material for prokaryotes & eukaryotes File
  • Submission assignment _Prokaryote and Eukaryotic cells 2023
• Topic 5. Cell structure
  

  Topic 5. Cell structure

  5. Cell structure 
      5.2 Cell organization and movement: cell membrane, cytoskeleton, cell adhesion, and cell junction
  

  • W 3^rdJuly 2024 : 10:00-12:00

  • Dr. Wanchana Phromkrasae (wanphrom@kku.ac.th)

  
  
• Topic 5. Cell structure
  

  Topic 5. Cell structure

  5. Cell structure

      5.3 Cell-cell interaction and cell to cell communication

  •  TH 4^th July 2024 : 09:00-10:00

  • Asst.Prof.Dr. Wises Namwat (wisnam@kku.ac.th) 

   

  • Cellular interaction and communication HANDOUT File
• Topic 6. Cell function (2)
  

  Topic 6. Cell function (2)

  6. Cell function 

     6.1 Membrane transport and ionic conductance
     6.2 Molecular trafficking (protein traffic, vesicular traffic, secretion and endocytosis)

  • TH 4^th July 2024 : 10.00-12.00

  • Asst.Prof.Dr.Weerapon Sangartit (weerasan@kku.ac.th)

                          
  

  
  
• Current Topic discussion I
  

  Current Topic discussion I

  Current Topic discussion I 
  

   (Related to lecture topics 1-4)

  M 8^th July 2024 : 13.00-16.00   

  Room 4401-4405, 4th floor, Academic and Research Laboratory Building (Wechwichakarn)

  Coordinator: Asst.Prof.Dr. Charupong Saengboonmee , Asst.Prof.Dr.Chadamas Sakonsinsiri and team
• Topic 7. Cell growth and development (3)
  

  Topic 7. Cell growth and development (3)

  7. Cell growth and development (3)   

  • W 10^th July 2024 : 09.00-12.00
  • Assoc.Prof. Dr.Kulthida Vaeteewoottacharn (kulthidava@kku.ac.th)

  • Assoc.Prof. Dr.Kanlayanee Sawanyawisuth  (kanlayanee@kkumail.com)
  • Assoc.Prof. Dr.Atit Silsirivanit (atitsil@kku.ac.th)
    

  
  

               
  

  7.1 Regulation of eukaryotic cell cycle  
  7.2 Signal transduction 
  7.3 Cell birth and lineage (stem cell) 

  • 7.1 Cell cycle handout Aj.Kanlayanee 9-10 am File
  • Eukaryotic cell cycle clip URL
  • How does cyclin-CDK work? clip URL
• Topic 8. Host immune system (5)
  

  Topic 8. Host immune system (5)

  8. Host immune system (5)

  • TH 11st July 2024 : 09:00-11:00
    
  • Asst.Prof.Dr.Arnone Nithichanon (Arnoni@kku.ac.th)

  
  
  
      

  
  

  
  

  
  

  
  

  8.1 Cell-microbes interaction

  8.2 Cell recognition
• Topic 8. Host immune system
  

  Topic 8. Host immune system

  8. Host immune system

     8.3 Innate immunity

  • M 15th July 2024 : 13:00-14.00 
  • Assoc. Prof. Dr. Sorujsiri Chareonsudjai  (sorujsr@kku.ac.th)

  
  
  

  
  
• Topic 8. Host immune system
  

  Topic 8. Host immune system

  8. Host immune system 

      8.4 Adaptive immunity (1.5)

  •  M 15th July 2024 : 14.30 - 16.00
  • Asst.Prof.Dr.Arnone Nithichanon (Arnoni@kku.ac.th)
    

           
  
• Questions and Answers (for topics 5-8)
  

  Questions and Answers (for topics 5-8)

  Not available
• Exam 2: Topics 5-8
  This topic
  

  Exam 2: Topics 5-8

  Exam 2 for topics 5-8  Cell structure-Host immune system (14 hr*5=70 points) 

  
  

  • M 24th July 2024 : 09.00-12.00

  • Asst.Prof.Dr.Opal Pitaksakulrat (opalpi@kku.ac.th)
  • Dr.Malinee Thanee
  • Venue: examination room, Research Laboratory Building, 7^th floor
    

  
  

   
• Topic 9. Molecular and cellular basis of diseases I (3)
  

  Topic 9. Molecular and cellular basis of diseases I (3)

  9. Molecular and cellular basis of diseases I (3)

  • TH 25^th July 2024: 09:00-12:00 
  • Dr.Malinee Thanee (malitha@kku.ac.th)

  
  

  9.1 Cell injury and cell death: mechanisms and consequences

  9.2 Programmed cell death and cellular senescence
• Topic 10. Molecular and cellular basis of diseases II (2)
  

  Topic 10. Molecular and cellular basis of diseases II (2)

  10. Molecular and cellular basis of diseases II (2)

  
  

  • W 31st July 2023 : 09.00-11.00
  • Dr. Kitti Intuyod (kittin@kku.ac.th)
    

  
  

  10.1 Diseases and causes of diseases
  10.2 Inflammation: acute and chronic
  10.3 Tissue repair and Angiogenesis
  
  

  
  

  
  

  
  

  • Handout for Molecular and cellular basis of diseases II - 66 File 10.3MB PDF document Uploaded 26/07/23, 00:46
• Topic 11. Cancer (3)
  

  Topic 11. Cancer (3)

  11. Cancer (3)

  •  TH 1st August 2024 : 09.00-12.00  
    
  • Assoc.Prof.Dr. Chawalit Pairojkul (chawpa@kku.ac.th)

  

  11.1 Definitions and characteristics of cancer

  11.2 Etiology and carcinogenic processes

  11.3 Molecular basis of cancer
  

  
  
• Topic 12. Maintenance of life and control mechanisms (3)
  

  Topic 12. Maintenance of life and control mechanisms (3)

  12. Maintenance of life and control mechanisms (3)

  • M 5th August 2024: 13.00-16.00
    
  • Asst.Prof.Dr.Putcharawipa Maneesai (putcma@kku.ac.th)

  
  

  

  12.1 Regulation of body metabolism

  12.2 Theories and biophysical factors and homeostatic mechanisms governing the life of an organism

  12.3 Homeostasis: Positive and negative feedback control

  
  
• Current Topic discussion II
  

  Current Topic discussion II

  Current Topic discussion II 

  W 7th August 2024 : 09:00 - 12:00

  Room 4401-4405, 4th floor, Academic and Research Laboratory Building (Wechwichakarn)

  Coordinator: Asst.Prof.Dr.Wises Namwat , Dr.Arporn Wangwiwatsin and team

    10-12 students and 1-2 tutors per group

        
  

  
  
• Questions and Answers (for topics 9-12)
  

  Questions and Answers (for topics 9-12)

  Questions and Answers (for topics 9-12)
  

  • TH 8^th August 2024 : 09:00-11:00
    
  • Staff: Malinee, Kitti, Chawalit, Putcharawipa

  
  
• Final Exam: Topics 9-12
  

  Final Exam: Topics 9-12

  Final Exam : Topics 9-12 (11 hr lecture x5 = 55 point) 

  • W 14th August 2024 : 09:00-12:00  
  • Venue: examination room, Research Laboratory Building, 7^th floor

  Let everyone good luck with the exam. The exam questions will be in English. Be well prepared!

  
  

  
  

  
  

  • EXAM-3 Results Announcement 2023 File 411.9KB PDF document Uploaded 25/08/23, 23:18